Recent studies have shown that ambient air pollution and lifestyle factors are associated with cardiometabolic diseases (CMDs) and dementia . However, the impact of air pollution and physical activity on dementia risk in individuals with CMDs remains underexplored. To address this, a study has investigated their effects on 438,681 individuals (median age: 56.5 years).
The study found that exposure to ambient air pollution increased the risk of mild cognitive impairment (MCI; 2.6-fold), all-cause dementia (1.7-fold), Alzheimer’s disease (AD; 1.3-fold), and vascular dementia (VD; 2.0-fold) in patients with CMDs compared to non-CMD individuals. Similarly, CMD patients with a low healthy lifestyle score (0 to 1) had a higher risk of developing MCI (2.9-fold), all-cause dementia (1.5-fold), AD (1.2-fold), and VD (1.9 fold) compared to non-CMD individuals. Notably, the risk of all-cause…
