Synopsis Aortic stenosis (AS) is an active disease, but the determinants of AS progression remain largely unknown. The present study aims at determining the impact of Fetuin-A on progression of calcific aortic valve stenosis. This week’s “MED FACT” discusses a clinical trial from International Journal of Cardiology, “Impact of Fetuin-A on progression of calcific aortic valve stenosis - The COFRASA - GENERAC study”. Authors: Naozumi Kubota et. al., Key Takeaways: Fetuin-A is a powerful inhibitor of ectopic calcification.
Objective: To determining the impact of Fetuin-A on progression of calcific aortic valve stenosis. Study Type: Prospective cohort Participants: 296 What Was The Need For This Study? Aortic stenosis (AS) is an active disease, but the determinants of AS progression remain largely unknown. Low levels of Fetuin-A, a powerful inhibitor of ectopic calcification, have been…
