Considering the major complications of current prostate cancer treatments such as erectile dysfunction, incontinence, bowel injury, and bleeding, a multicenter, randomized trial was conducted to evaluate the effect of focal vs extended irreversible electroporation (IRE) in localized low-intermediate risk prostate cancer patients. Here’s a quick summary. Published in J. Urol., 2023. Authors: de la Rosette J, Dominguez-Escrig J, Zhang K, et al.
What was the need for the study? Focal therapy has emerged as a new avenue for treating localized low-intermediate risk prostate cancer, with reduced adverse effects while retaining beneficial oncologic control. Irreversible electroporation (IRE), a nonthermal ablation modality, has also proved to be effective in destroying tumor cells. However, studies related to the adoption of IRE as a valid focal ablative therapy modality are limited due to the…
