Myocardial Work After Valve Intervention: Does Iron Status Matter? Severe aortic stenosis places significant pressure overload on the left ventricle, making early detection of subtle dysfunction crucial. This study explored whether iron deficiency influences left ventricular myocardial work in patients undergoing transcatheter aortic valve implantation, using advanced noninvasive indices beyond conventional measures like ejection fraction. In 100 patients evaluated before and one year after the procedure, valve intervention improved hemodynamics across the cohort.
While traditional parameters such as ejection fraction and global longitudinal strain remained stable, myocardial work indices—including global work index and constructive work—declined significantly over time. Interestingly, the impact of iron deficiency varied depending on how it was defined. Using conventional definitions,…
