Total and supplemental vitamin C intake is associated with a significantly elevated risk of kidney stones in men, according to a new study. In a prospective cohort analysis, Pietro Manuel Ferraro, MD, of Columbus-Gemelli University Hospital in Rome, Italy, and colleagues found that total vitamin C intake of 90–249, 250–499, 500–999, and 1,000 mg/day or higher was associated with a 19%, 15%, 29%, and 43% increased risk of kidney stones among men compared with an intake below 90 mg/day (reference). The researchers found no association between total vitamin C intake and stones among women.
Additionally, Dr. Ferraro's group found that high supplemental vitamin C intake was associated with an increased risk of kidney stones in men, but not women. Supplemental vitamin C intake of 1,000 mg/day or more by men was associated with a significant 19% increased risk of kidney stones compared with no…
