Classical pharmacology texts in the Siddha system of medicine, native to Tamil Nadu, mention the potential role of lemon in managing certain mental health conditions. A recent observation involved a young girl showing early symptoms such as irritability and talking to herself when alone—features that can sometimes be seen in early stages of psychiatric conditions. Her routine activities such as eating, sleeping, and personal care remained normal. Based on traditional knowledge, her parents were advised to give her lemon juice prepared from two fruits twice daily.

Within ten days, a noticeable improvement in her behavior and overall calmness was observed. Historically, villages have also practiced applying concentrated lemon juice on the head of individuals experiencing mental disturbances. These traditional observations highlight the need for scientific research to explore the potential…