A 17-year-old female presents with fever (T39.0), vomiting and diarrhoea, widespread muscle aches and a confluent erythematous macular rash resembling sunburn all over her body. She is persistently hypotensive (BP 85/35 mmHg) despite 2L of crystalloid fluid resuscitation. Her laboratory results are: Full Blood Picture Hb 130 (120-155 g/L) WBC 18.3 (4.5-13.0 x 10E9/L) Plt 250 (150-400 x 10E9/L) Urea and Electrolytes Na 138 (134-146 mM) K 3.8 (3.4-5.0 mM) urea 5.0 (3-8.9 mM) Cr 160 (<75 microM) Other Investigations CK 425 (30-170 IU/L) Alb 28 (35-50 g/L) LFTs unremarkable CRP 73 (<10 mg/L) Blood cultures, throat swabs, and urine MCS were sent and the results are pending. She completed menstruating the day before and was otherwise previously well.
What is the diagnosis? What would be the treatment? *This case is from Docplexus Editorial Team for educative purpose only.
