Eosinophilic esophagitis (EoE), a chronic inflammatory disorder, has recently been recognized as an independent clinical entity. The incidence and prevalence of this autoimmune disorder has steeply increased in the last few decades. The pathophysiology of EoE encircles the genetic, environmental and patient’s immune factors. Its management is particularly challenging with reference to the treatment objectives and the end points.
Introduction Eosinophilic esophagitis (EoE) is a chronic and progressive inflammatory disorder of autoimmune origin that presents symptoms of esophageal dysfunction (food impaction) along with the eosinophilic infiltration of the esophageal mucosa. Around 30-60% of individuals with EoE complain of heartburn and 8-44% report non-cardiac chest pain. The diagnostic approaches evaluate both clinical and pathological findings, and include symptoms related to…
