Retinopathy of prematurity (ROP) is one of the most common causes of visual loss in childhood. Despite many advances in different areas, such as screening and treatment of ROP, there is a lack of standard medical therapy. Conventional surgical interventions bring along their side effects and novel medical therapies are not yet approved for use in premature infants. The article presents an overview of various approaches to manage ROP at different stages.

Retinopathy of prematurity (ROP) is a retinal vasculature proliferation disorder that occurs in preterm infants (less than 31 weeks of gestation). ROP can produce critical impairments of vision, including blindness. It continues to be an area of major concern, despite outstanding advancements in the neonatology. Based on its severity ROP can be categorized into five stages: Stage I, mildly abnormal blood vessel growth, to stage V,…