Prevalence of Chronic Kidney Disease (CKD) has increased in India, at the same time advancement in the medication of CKD have permitted patients to live longer. Accurate medication dosing is required for patients with CKD to avoid adverse drug reactions, prevent additional renal injury and to optimize patient outcomes. In CKD almost half of the medications are eliminated via kidney because of reduced kidney function. In addition to CKD, many patients also suffer from hypertension, diabetes and heart failure.
Hence, sometimes medication of all these co-morbidities do not coordinate. Change in renal function changes the bioavailability, distribution, metabolism, and elimination of drugs. Adverse medication-related outcomes in CKD: Kidney damage (including Acute kidney injury) Accelerated kidney function loss End-stage kidney disease Hyperkalemia Hypercalcemia Hypoglycaemia Bleeding…
