COVID-19 is undoubtedly a global concern at present. Mass vaccination schemes, monoclonal antibodies, and drug repurposing programs have curbed the rapid transmission. However, the mutant variants can evade vaccine-induced and natural immunity, thereby spreading faster than the earlier forms of the virus. Researchers have recently evaluated the effectiveness of memory B cells produced in response to mRNA vaccine on the severe acute respiratory syndrome coronavirus disease 2 (SARS-CoV-2) variants.
The findings of this study are published in the journal Immunity. 1 What are these mRNA vaccines and how do they work? Vaccines conventionally are attenuated viral strains which recognize the cell surface protein and induce a safe immune response. However, in an already infected individual, the attenuated strain may interact with the virulence factor of the virus and induce pathogenicity.…
