Nasal obstruction is the commonest symptom reported in specialist clinics among patients with upper respiratory tract disease like nasal polyposis, which affects up to 4% of the population. Nasal obstruction in these patients is associated with edema formation secondary to inflammatory processes.

Several studies have suggested the presence of eosinophils and related mediators in patients with non-allergic or allergic nasal polyposis. Important inflammatory mediators include: ·       Interleukins: IL-4, IL-5, IL-6, IL-8, IL-10 ·       TNF-α ·       Regulated on activation, normal t-cell-expressed and secreted (RANTES) ·       Granulocyte-macrophage colony-stimulating factor (GM-CSF) ·       Granulocyte colony-stimulating factor, ·       Eosinophil cationic protein (ECP) ·       Eotaxin ·       interferon (IFN)-γ Additionally, elevated levels of metalloproteinases and damage of…