New guidance on the management of diabetes and its complications in pregnancy has been recently issued by the UK based, the National Institute for Health and Care Excellence (NICE). This is the first update on this topic since 2008 and, most important, since the landmark multinational Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study was published (N Engl J Med. 2008;358:1991-2002).
HAPO, published in 2008, was the first study to conclusively establish a relationship between elevated maternal glucose concentrations and undesirable perinatal outcomes in women not previously diagnosed with diabetes. Besides advising on gestational diabetes, the new NICE guidelines also address the management of type I and type II diabetes both preconception, during pregnancy and birth, and after delivery, as well as neonatal care. NICE has opted for a 101-mg/dL cutoff to diagnose gestational…
