Nipple-sparing mastectomy (NSM) is as oncologically safe as skin-sparing mastectomies (SSMs) or modified radical mastectomies (MRMs) in carefully selected women with early-stage breast cancer, a meta-analysis concludes. The findings were presented at the American Society of Breast Surgeons (ASBS) 16th Annual Meeting, in Orlando, Florida, and were highlighted at a press briefing. Lucy De La Cruz, MD, University of Miami Miller School of Medicine, in Florida, reviewed 19 studies that included 5276 patients who had undergone either an NSM, an SSM, or an MRM.
Six studies compared overall survival (OS) in women undergoing an NSM vs either an SSM or an MRM. On the basis of the results from these 6 studies, there was a 2.5 risk difference in OS in favor of the NSM compared with the other two procedures. Three studies compared disease-free survival (DFS) in women who had undergone an NSM vs…
