Nitrous oxide (N₂O) is a commonly used anesthetic gas in operation theatres. However, prolonged exposure to this occupational pollutant can have serious long-term health consequences for OT staff, anesthesiologists, and surgeons—more so in individuals with vitamin D deficiency. How Nitrous Oxide Causes Harm Nitrous oxide (N₂O) deactivates vitamin B12 by irreversibly oxidizing the cobalt atom within the vitamin. This inactivates the enzymes responsible for DNA synthesis and myelin (nerve coating) production.
Whether used medically or recreationally, it can rapidly induce severe, functional B12 deficiency and neurological damage. The Danger: Functional Vitamin B12 Deficiency Even if your serum B12 blood test returns a "normal" level, nitrous oxide exposure can cause a functional deficiency. The gas destroys the body's ability to actually use the B12. This interference disrupts two…
