In t he last few years use of polymeric medical devices has increased considerably. However, its long term applications are often found to be associated with biofilm formation, which gives rise to nosocomial infections and thus contributing to the considerable amount of morbidity and mortality. In this regard, antibiotic therapy can offer a very limited solution because of the increased incidences of antibiotic resistance. Hence, noble metal like silver has been studied as an alternative option as a bactericidal agent for its low toxicity and minimal risk due to exposure.
This article discusses the role of silver as an antimicrobial agent in the case of nosocomial infections. In recent years, biocompatible polymeric devices have found their place in the medicinal technology. However, their long-term application is associated with bacterial colonization, biofilm formation, and…
