The exact pathophysiology of manifestations due to anemia is not well understood however it may be due to hypoxia associated with anemia. Ocular changes in patients of anemia are as follows:  Conjuctival pallor and hamorrghes Retinal changes in particular aneamic retinopathy is a well documented complication of aneamia Retinal findings are Intra retinal hemorrghes Roth spot hemmorghes Cotton woll spots d retinal exudate Retinal exudate Venous dilatation Optic nerve pallor Share your views.