Wilsons disease also commonly known as hepatolenticular degeneration is a genetic disorder in whch copper builds up in the body due to impairment of enzyme celluloplasmin which is responsible for copper metabolism so copper granules get deposited in the liver, brain and peripheral part of the desmets membrane of the cornea. Liver manifestations are in the form of vomiting, weakness, fluid retention in abdomen swelling of legs yellowish skin and itching. Brain-related disorders are tremors, muscle stiffness, trouble in speaking, personality changes.
Incidence is 1 in 30 000 age is from 5 to 35 years. Ophthalmic examination slit lamp examination copper gets deposited on the peripheral part of destments membrane in the form of golden brown ring called as KF ring one may also get sunflower cataract in these patients though rare tests ultrasound abdomen to exclude liver pathology ophthalmic…
