A 60-year-old chronic smoker and tobacco chewer developed a curved, horn-like projection at the right oral commissure over 7-8 months, reaching 2-3 cm with a hard base and tapering tip, accompanied by a painless yellowish lesion causing mild discomfort. Excisional biopsy revealed hyperkeratotic stratified squamous epithelium with hair follicles and cutaneous appendages atop loosely arranged connective tissue containing sebaceous glands, eccrine glands, fatty tissues, hyaline material, and chronic inflammatory cells. This rare dermoid cyst-cutaneous horn combination at the oral commissure highlights smoking-related diagnostic challenges in perioral lesions requiring biopsy for premalignant/malignant exclusion.
Biopsy early don't let oral horns hide deadly secrets! Interested in more reading the case Click Here ##Reference## Borade, Palak; Vikey, Ashok; Joshi, Jaya; Arora, Sakshi.…