Prostate-specific antigen (PSA)>4.5 ng/ml and the number of positive cores > 2 in low-risk prostate cancer (PC) were associated with the presence of adverse pathologic features (APF) and patients with such records should be considered carefully to provide active surveillance reported a new study published in the BMC Cancer. The study suggested that PSA plays an important role in the prediction of APF after radical prostatectomy (RP). Among the study population of 546 patients, extracapsular extension (ECE), seminal vesicle invasion (SVI), and positive surgical margins (PSM) were detected in 199 (36.4%), 8(1.5%) and 179 (32.8%) cases respectively.
The study findings revealed that PSM had a significant correlation with preoperative high PSA levels and number of positive cores obtained. Similarly, ECE and SVI were also significantly correlated with PSA levels and number of positive cores.…
