Punch Biopsy for Assessing Tissue Damage in COVID-19 Patients

  Scientists have identified simple punch skin biopsy as an alternative technique to study microvascular and tissue changes related to COVID-19. They were able to compare the blood vessel pathology of patients with severe and mild COVID-19, which, until now, could only be carried out using autopsy samples. The findings of this study are published in The American Journal of Pathology . Do you think it is possible to grade other microvascular disorders using the punch skin biopsy technique?

Reference: Laurence J, Nuovo G, Racine-Brzostek SE, Seshadri M, Elhadad S, Crowson AN, Mulvey JJ, Harp J, Ahamed J, Magro C. Pre-mortem skin biopsy assessing microthrombi, interferon-I antiviral and regulatory proteins, and complement deposition correlates with COVID-19 clinical stage. The American Journal of Pathology. 2022 May 28.