Diabetic nephropathy (DN) remains the leading cause of end-stage renal disease globally, affecting approximately 30–40% of individuals with diabetes and posing a significant health burden. Its pathogenesis is complex and multifactorial, including chronic hyperglycemia, hypertension-induced hemodynamic changes, oxidative stress, and inflammation, all of which contribute to glomerular injury, basement membrane thickening, albuminuria, and progressive renal dysfunction. Major risk factors contributing to the development and progression of DN include hyperglycemia, hypertension, obesity, dyslipidemia, smoking, advanced age, male sex, race/ethnicity, and genetic predisposition.
Here's a quick question to refresh your knowledge on diabetic nephropathy! References : Cureus, Biomedicines, and BioMed Research International ##Disclaimer## The content provided on Docplexus is intended for…
