Recurrent aphthous ulcer (RAU) is a clinical condition characterized by painful ulcer with different size affecting the mucosa of the oral cavity. Its etiology and pathogenesis are not clearly known and the diagnosis is based on the clinical picture. These lesions may be classified into minor, major, and herpetiformis.

Although RAUs are self limited, this lesion causes pain and discomfort and interferes in eating, speaking, and swallowing which leads to poor quality of life. Early and effective treatment of RAUs ulcer minimizes the discomfort in speaking and painful swallowing. Present review of literature aims to discuss recurrent aphthous ulcer in detail.