A novel method of bacterial single-cell RNA sequencing developed by German researchers Help us to understand the tricks that bacteria use to develop antibiotic resistance New possibilities in infection biology research Published in the “Nature Microbiology” journal Bacteria demonstrate numerous mechanisms of resistance to antibiotic treatment or an attack by our immune system. Recently, scientists from a research institute in Germany have developed a novel approach for reading the activity of hundreds of genes in a single bacterium by sequencing its RNA. Using bacterial single-cell RNA sequencing, it will now be possible to elucidate the mechanism of antibiotic resistance and design tailor-made drugs.
This groundbreaking work is a huge leap forward in combating antibiotic resistance. Previously, single-cell RNA sequencing was only achieved with much bigger cells of other organisms. …
