A majority of traumatic brain injury (TBI) cases reported to the emergency department fall into the mild traumatic brain injury (mTBI) category. The current practice of predicting mTBI is based on clinical and brain CT scan results. These scans are expensive and often lead to unnecessary radiation exposure. Therefore, there is an increasing need to identify newer reliable biomarkers that can accurately and rapidly predict the need for imaging and help clinicians in spotting those patients in need of further assessment.

Several such biomarkers have been studied over the recent years, such as GFAP and S100Ξ² 1 . A recent study from Iran has shown that the need for imaging can be predicted by determining serum aldolase C levels within the first three hours after head trauma. Study details Key findings The brain CT scan findings showed a positive TBI in 30 of the patients and negative TBI in…