A 67-year-old previously healthy woman was evaluated for dry cough of 3 weeks’ duration. There was no hemoptysis, chest pain, or fever. She experienced anorexia and weight loss of 2 kg during the previous month. She denied the use of substances of abuse or smoking. Physical examination was unremarkable. A chest radiograph did not reveal any abnormality.

A contrast-enhanced computed tomography of the thorax showed a defect in the anterior wall of the right main bronchus [Figure 1a and b, arrow]. The pulmonary parenchyma was normal, and there was no mediastinal or hilar lymphadenopathy. Flexible bronchoscopy showed a deep ulcer with a yellowish flattened base in the anterior wall of the right main bronchus [Figure 1c and Supplemental Video]. Bronchial washings were obtained without any complications. Initially, we performed EBB from the edge of the lesion and base of the lesion. However,…