Side Effects Of Nitrous Oxide In Anaesthesia Nitrous Oxide (N 2 O) with oxygen causes atelectasis in poorly ventilated lung than O 2 alone N 2O  causes increases pulmonary artery pressure in patients with PIH It inhibits pulmonary Hypoxic vasoconstriction reflex (HPV) leading to increased intrapulmonary shunting, increased FiO 2 counteract this effect. N 2 O is contraindicated in presence of pulmonary Bullae which may rupture leading to pneumothorax, hemodynamic instability, bronchopleural fistula.

precipitate Diffusion Hypoxia in patients with reduced ventilatory reserve after reversal. It causes cerebral depression without affecting vasomotor, respiratory centres caution adequate oxygen  Contracted in any closed gas-filled  spaces like pleural, pericardial, & peritoneal, in condition like intestinal obstruction, obstruction of middle ear, Arterial air embolism, Decompression sickness…