Severe ocular complications of Stevens-Johnson syndrome continue to pose significant long-term challenges for survivors, but innovative ocular surface reconstruction techniques are helping patients regain comfort, function, and vision. At the Singapore National Eye Centre, senior consultant Dr. Ong Hon Shing and colleagues are using a combination of mucous membrane grafting and limbal stem cell transplantation to treat patients with devastating ocular sequelae following Stevens-Johnson syndrome.
One such patient was 30-year-old Fikriyah Mohamad Nor, who developed Stevens-Johnson syndrome in 2018 after an unexplained febrile illness. Although the acute phase resolved, extensive ocular involvement left her with severe chronic inflammation and progressive eyelid margin keratinization. The resulting changes transformed the normally moist eyelid margin into a rough, keratinized surface that…
