Selective Serotonin Reuptake Inhibitors (SSRIs) are commonly prescribed for the treatment of post-stroke depression. About 16 meta-analysis studies suggest that SSRIs increase the risk of intracranial hemorrhages. The risk of intracranial hemorrhage (ICH) associated with selective serotonin reuptake inhibitors (SSRIs) increase with the strength of the agent used. This article briefly overviews about the relation between SSRIs and ICH risk. It seems that approximately two third of SSRI prescriptions are for depression.
Some recent investigations suggest that there is a positive correlation between SSRIs and ICH risk. Hence, to spread awareness this article is attempted here. Predictable mechanism of SSRI for increased risk of ICH: SSRI inhibit the serotonin transporters in neuron as well as platelets. This decreases concentration in these cells, especially in platelets. Hemostasis is the…
