Pyogenic granuloma (PG) is a benign vasoproliferative lesion often misdiagnosed as malignancy when presenting as a longstanding ulcer on the tongue . Zhang et al. (2025) describe a 75-year-old woman with a 5-year ulcerative protrusion on the lateral tongue margin, initially suspected as carcinoma but confirmed histologically as PG. Instead of surgery, two local triamcinolone acetonide injections with adjunctive bFGF and antiseptic rinses led to complete healing within 4 weeks, with no recurrence up to 1 year.
This case demonstrates the importance of pathology in ruling out malignancy and supports corticosteroid injection as a minimally invasive alternative to surgical excision in select oral PGs. To read more ; Click here Could steroids replace surgery for challenging oral PGs? ##Reference## Zhang Y, Mao Q, Wang Y, Sun F, Liu C. Corticosteroid injection for pyogenic granuloma of the…
