Key takeaways: Sucralfate significantly improves the quality of life (QoL) in gastroesophageal reflux diseases (GERD) patients. It is efficient and safe, with limited side effects. Sucralfate can be administered as primary therapy or an add-on to the drug of choice for treating GERD. Gastroesophageal reflux disease (GERD) has a noticeable impact on the quality of life. Among the available GERD treatments, acid suppression is considered the front-line treatment.
Proton pump inhibitors (PPIs) suppress acid and heal esophagitis, along with relieving symptoms. However, about one-third of patients fail to respond to acid suppressors. 1 This demands alternative therapies focussing on mucosal protection to attenuate the corrosive acid effects. Sucralfate, a salt of sucrose sulfate and aluminum hydroxide, confers mucosal protection. 1 Let us understand the common myths and relevant facts about…
