Recent studies suggest that nocturnal hypertension during sleep increases the risk of cardiovascular disease (CVD) and mortality. However, the association between supine hypertension and CVD risk, independent of seated hypertension, remains unclear. To investigate this, a study has examined this association in 11,269 individuals (mean age: 53.9 years) without CVD. The study found that supine hypertension without seated hypertension was strongly associated with increased risks of coronary heart disease (CHD), heart failure, stroke, fatal CHD, and all-cause mortality over a median follow-up of 25.7 to 28.3 years.
Notably, these results remained consistent regardless of antihypertensive use. Furthermore, supine hypertension alone was associated with risks similar to hypertension in both positions and greater risks than seated hypertension alone, except for fatal CHD. These findings…
