Percutaneous coronary intervention (PCI) guided by the ideal method i.e. fractional flow reserve (FFR) using the current best stent (durable polymer zotarolimus-eluting stents - Resolute Integrity or Resolute Onyx, Medtronic) did not meet non-inferiority for one-year adverse events compared to coronary artery bypass grafting (CABG) in patients with three-vessel coronary artery disease, primary results of the FAME 3 (Fractional flow reserve versus angiography for multivessel evaluation) trial have shown. It has been shown in innumerable studies and trials that patients with three-vessel coronary artery disease have been known to have better outcomes with coronary artery bypass grafting (CABG) than patients with percutaneous coronary intervention (PCI).
However, studies in which PCI is guided by the measurement of fractional flow reserve (FFR) have been lacking. In this multicenter,…
