This multi-institutional study—the largest to date evaluated 448 patients with sinonasal inverted papilloma (SNIP) across seven high-volume rhinology centers from 2002 to 2023. The analysis demonstrated that while most tumors lacked dysplasia, severe dysplasia significantly increased recurrence risk, particularly in multifocal attachment patterns. Unifocal tumors consistently showed better recurrence-free survival across non-severe dysplasia categories, underscoring the prognostic role of attachment morphology.
The authors propose a streamlined two-tier dysplasia grading system to enhance diagnostic consistency and refine patient counseling. Overall, severe dysplasia emerges as a critical marker for aggressive surveillance and meticulous surgical planning. To explore the full dataset and understand how dysplasia reshapes the prognosis of sinonasal inverted papilloma, read the complete…
