Background: Preeclampsia is a major cause of maternal, fetal and neonatal morbidity and mortality, particularly in developing countries. Considering the burden of preeclampsi a and its associated complications, it is important to understand the underlying risk factors and mechanisms involved in its etiology. There is considerable interest in the potential for dietary long chain polyunsaturated fatty acids (LCPUFA) as a therapeutic intervention to prevent preeclampsia, as they are involved in angiogenesis, oxidative stress, and inflammatory pathways.
Methods: The REVAMP study (Research Exploring Various Aspects and M echanisms in Preeclampsia) followsa cohort of pregnant women from early pregnancy until delivery t o examine longitudinally the associationsof maternal LCPUFA with clinical outcome in preeclampsia. A multisite centre for advanced research wasestablished and pregnan t women…
