Therapeutic Apheresis (TA) has been successfully introduced in a variety of autoantibody-mediated diseases. In dermatology, TA is increasingly applied as a support treatment for severe and/or refractory autoimmune bullous diseases. This article, which is written based on a review, focuses on the several diseases where TA has proven to be beneficial.
The autoimmune dermatology diseases are characterized by autoantibodies mediated against structural proteins of the skin and/or mucous membranes. Autoimmune blistering diseases have a high morbidity and mortality. According to the depth of split formation, the disorders can be classified as intraepidermal blistering pemphigus, such as Pemphigus Vulgaris (PV), pemphigus foliaceus, and paraneoplastic pemphigus, and as subepidermal blistering pemphigoid diseases, such as bullous pemphigoid (BP), pemphigoid gestations, and dermatitis…
