A 30-year-old woman with known type 1 diabetes for 12 years. She visits her GP complaining of tiredness and weight gain. Her HbA1c levels over the past 7 years have ranged between 6.4 and 7.1%, but her most recent test showed an HbA1c of 8.3%. Her diet has not changed but doing less exercise due to extreme fatigue. The dose of her insulin has not changed and she continues in her current job as a teacher and has no family problems or social issues of note.

On further questioning, she told that her skin is getting very dry, is feeling constantly cold and her hair is becoming coarse and brittle. Also, she has had recent problems with menstrual irregularities and has been constipated. What is the probable diagnosis? * This case is from Docplexus Editorial Team for educative purpose only Source: Clincal cases uncovered-endocrinology and diabetes