Some times in cases of hypokalemia inspite of oral or I/V potassium supplementation there is no adequate rise in serum potassium. In such cases, we should think of coexisting magnesium deficiency or hyperaldosteronism. If hypertension is associated with hypokalemia it points towards hyperaldosteronism and spironolactone will both correct hypokalemia as well as control BP. In some cases, magnesium supplementation by I/V route with I/V fluids will correct serum potassium.

While giving I/V magnesium we have to keep a watch on BP. Both these conditions are not uncommon. Spironolactone is a good drug in cases of resistant hypertension. Share your line of action for Hypokalemia?