For the clinical management for gastrointestinal disorders, such as inflammatory bowel disease, Crohn's disease and ulcerative colitis, patients are generally supposed to maintain a drug-infused enema in the colon for hours for the medication to be absorbed. This can be very difficult for patients with diarrhea and incontinence, so something that can reduce the duration of the procedure is the need of the hour. Besides nanomedicine, ultrasound also assists better and fast absorption of the drug in GI tract.
Inflammatory bowel disease is an umbrella term that covers Crohn's disease (CD), ulcerative colitis (UC) and indeterminate colitis (IC). These painful diseases involve an abnormal response by the immune system that damages the lining of the digestive system, causing inflammation and ulceration, severe abdominal pain, diarrhea, bloody stools, fatigue and weight loss. Origin of this…
