Management of Left Main Disease: An Update. The following are key points to remember from this review article on the management of left main disease: 1- A severe narrowing of the left main coronary artery (LMCA) jeopardizes a large area of myocardium and increases the risk of major adverse cardiac events. 2- In general, management strategies for LMCA disease include coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI).
3- PCI offers more rapid recovery and a lower early adverse event rate, whereas CABG offers a more durable procedure. 4- The largest of six LMCA trials comparing PCI with CABG recently reported that in patients with site-reported low or intermediate anatomical complexity, PCI was noninferior to CABG with respect to the composite of death, stroke, or myocardial infarction at 3 years. This result was obtained on a background of contemporary…