Researchers at the Department of Otolaryngology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, have addressed the complications associated with the postoperative management of chronic rhinosinusitis. The study aimed to find the efficacy of self-crosslinked hyaluronic acid (scHA) as a sustained-release carrier for the steroid budesonide when applied topically. Study details Interventional randomized clinical trial The study included 30 participants who had undergone FESS after being diagnosed with chronic rhinosinusitis with nasal polyps (CRSwNP).
The control group received a single dose of scHA, and the treatment group received a combination of scHA/ budesonide post-operation. The patients were examined 2, 4, and 12 weeks after the operation. The combination of scHA gel with budesonide was more effective in endoscopic scoring and mucus evaluation than treating with…
