The benefits of vitamin D in prevention of skeletal disorders have been well-recognized but the recent studies demonstrated that the beneficiary effects are beyond bone health to tumor regression. In the present study, researchers aimed to evaluate the association between Vitamin D and liver cancer in a large cohort study. Study Design: Nested case-cohort study within the Japan public health center-based prospective study cohort. 3301 incident cases of cancer were included after exclusion of participants with insufficient plasma sample for 25-hydroxyvitamin D assay, non-melanoma skin cell cancers and missing information on covariates.
4044 sub-cohort participants were selected from 33,736 base cohort. Methods Baseline plasma 25-hydroxyvitamin D concentration was measured by two-step sandwich immune assay method Lumipulse G 25-OH Vitamin D assay. Participants were divided by…
