Acute kidney injury (AKI) affects an estimated 40-70% of critically ill infants and is linked to increased morbidity and mortality. Suspected predisposing factors include asphyxia, hypovolemia, heart failure, sepsis, and respiratory distress syndrome. Owing to the varying severity of AKI and related mortalities worldwide, two main criteria were used to define and classify AKI: Risk, injury, failure, loss of kidney function, and end-stage kidney disease (RIFLE) classification and acute kidney injury network (AKIN) criteria. RIFLE was launched in 2004 and was then modified into AKIN in 2007. The major differences identified between these two criteria are as follows: According to the RIFLE criteria, AKI can be divided into the following three categories: A.

Risk B. Injury C. Failure According to the AKIN criteria, AKI can be divided into the following broad categories: A. Stage I B. Stage…