In patients with uncontrolled hypertension despite three antihypertensives, including a diuretic, secondary causes should always be considered. One important possibility is primary aldosteronism, which often presents with resistant hypertension and characteristic biochemical changes. Screening with the aldosterone–renin ratio (ARR) is recommended, particularly in patients with adrenal incidentalomas or difficult-to-control blood pressure. Early recognition allows for targeted treatment, which may even be curative, whereas delays can lead to progressive cardiovascular damage.
Test your knowledge with this quick question and see if you can spot the key electrolyte clue. Reference : The Journal of Clinical Endocrinology & Metabolism ##Disclaimer## The content provided on Docplexus is intended for educational purposes only. While we strive to ensure its accuracy, we make no explicit or…