A simple blood test could predict rheumatoid arthritis risk up to 16 years before the onset of the painful and debilitating condition, Oxford scientists say. Rheumatoid arthritis (RA) occurs when, during inflammation, some proteins become altered via a process known as citrullination. These modified proteins can induce an immune reaction from one's body, whose antibodies can turn on itself manifesting the disease called arthritis. The exact cause of RA is still unknown, it could result from a combination of genetic and environmental factors.

Age and sex, genetics, smoking, oral contraception, and lack of exercise are some risk factors. Arthritis is estimated to affect up to 1% of the population of the developed world and is almost three times more likely to affect women than men. The percentage is higher in developing countries like India. The blood test looks for antibodies that…