A 35-year-old nurse is troubled by a persistent cough and wheeze, which gets worse as the day goes by. She was admitted to the hospital thrice with acute exacerbations of this problem in the last three years. Her problem is perceived to be persistent and troublesome.

What is your diagnosis for this patient and how will you treat her? * This Case Challenge is from the Editorial Team of Docplexus and is meant for educational purposes only.