The SARS-CoV-2 pandemic, which claimed so many lives globally, has highlighted the vulnerability of human society and the healthcare system to outbreaks from emerging pathogens. While accurately predicting what will trigger the next pandemic is not feasible, identifying effective broad-spectrum treatments can help prevent such future pandemics. Now, a team of researchers has identified the potential board-spectrum antiviral drugs that can target several families of RNA viruses, including Chikungunya virus (CHIKV), Dengue virus, West Nile virus, and Zika virus, which are considered potential agents for future pandemics.
In their study, the researchers found that the cyclic dinucleotide (CDN) Stimulator of Interferon Genes (STING) agonists were the most potent and comprehensive antiviral agents. A single dose treatment of cAIMP, a STING agonist, effectively prevented and mitigated the…
