An 11-year-old female without significant past medical history was presented with symptoms indicative of hyperthyroidism such as weight loss and heat intolerance. Her school performance also got affected as a result of it. Family history is significant for thyroid disease in both grandmothers (both on thyroid replacement therapies).
The clinician ordered thyroid function tests including Free T4, T3, TSH, anti-TSH receptor antibodies, antithyroglobulin and antithyroid peroxidase antibodies. The results of the tests performed are as follows: Free thyroxine (FT4) 2.87 ng/dL (Prepubertal 0.73-1.77 Pubertal/Adult 0.73-1.84) Total triiodothyronine pediatric (T3) 374.00 ng/dL (123-211) Thyroid-stimulating hormone (TSH) <0.018 uU/ml Thyroxine (T4) 18.2 ug/dL (5.0-12.0) Antithyroglobulin antibodies >3000 IU/ml (Negative <60 IU/mL Equivocal 60-100IU/mL Positive >100 IU/mL) Antithyroid…
