A 51-year-old woman presents with an 8-month history of bloating and abdominal discomfort, both relieved somewhat after a bowel movement. She denies nausea or vomiting. She has been prone to constipation most of her adult life and has a history of dysmenorrhea. The patient reports no prior abdominal surgeries, medications, or weight loss. Colonoscopy performed an year back (because her father, aged 56 years, has colon cancer) was normal.

Findings on examination are normal. Laboratory findings Hemoglobin, 10.7 g/dL Mean corpuscular volume, 76 fL Ferritin, 6 μg/L Tissue transglutaminase (tTG) IgA, normal What could be the differential diagnosis and possible management for this patient? *This case is by Docplexus editorial team for educative purpose only. Source NCBI