A 60-year-old female with no comorbidities noticed the sudden appearance of multiple petechiae on her extremities and mild epistaxis. She had no other symptoms and denied taking any medications. A CBC performed by her primary-care physician identified an isolated thrombocytopenia with a platelet count of 30 x 109/L. She was referred to a hematologist who did an extensive work-up revealing no other significant abnormalities.
A bone marrow biopsy was unremarkable, apart from numerous megakaryocytes. She was given a diagnosis of immune thrombocytopenic purpura (ITP). Considering the above investigations, which cytokine might be responsible in the pathogenesis of thrombocytopenia in ITP? *This case is from Docplexus editorial team for educative purpose only Source: Cases in Hematology Stay connected, the answer will be posted in 48 hrs
